Covered Topics

In this seminar you will learn how bioinformatics approaches can be used to study the molecular mechanisms of cancer and thereby improve our knowledge of biological processes that are responsible for tumor initiation and progression. Each participant will present a research paper that covers an interesting computational method to categorize tumors, to identify pathogenic mechanisms, or to find novel biomarkers that improve the diagnostic of the disease.

The seminar will be held as a block seminar the week before the lectures start.


Prof. Dr. Hans-Peter Lenhof

Teaching Assistant

Prerequisites Important

Conditions for Certificate


In order to participate in the seminar you are required to attend the first meeting.
There the topics are distributed. No prior registration or reservation is possible.
Please confirm your participation in the seminar until 2018/02/09 via mail to
Also, you have to register in HISPOS until 2018/02/16.

# Paper Authors Speaker Supervisor
1 A weighted exact test for mutually exclusive mutations in cancer Leiserson et al. - -
2 A modular framework for gene set analysis integrating multilevel omics data. Sass et al. Carolin Mayer Lara Schneider
3 Inferring Regulatory Networks from Expression Data Using Tree-Based Methods Huynh-Thu et al. Nadja Grammes Tim Kehl
4 IGSA: Individual Gene Sets Analysis, including Enrichment and Clustering Wu et al. Jeenu Joy Tim Kehl
5 Metagenes and molecular pattern discovery using matrix factorization Brunet et al. Farzaneh Khojasteh Lara Schneider
6 Similarity network fusion for aggregating data types on a genomic scale Wang et al. - -
First Meeting
Friday, 2018/01/26, 5 p.m., building E2.1, room 406
Essay Deadline
Thursday, 2018/02/22, 11:59 p.m.
Slides Deadline
Thursday, 2018/03/15, 11:59 p.m.
Wednesday, 2018/04/04, 9 a.m. - 3 p.m., building E2.1, room 406

Checklist for slides

Checklist for report

Supplementary material

  1. How to give a scientific presentation (Susan McConnell) PDF
  2. The Craft of Scientific Presentations (Michael Alley)